Reid Group Research
A data-driven understanding of process chemistry.
Reaction Mechanisms
We use the tools of Physical Organic Chemistry to study reaction mechanisms of industrially-relevant reactions.
Enabling Technology
We develop computer programs to help chemists extract more information during reaction monitoring.
Process Safety
We work with safety staff in chemical manufacturing to develop new safety training methods.
Latest group photo: February 2023
Latest papers:
Computer Vision as a New Paradigm for Monitoring of Solution and Solid Phase Peptide Synthesis
Chem. Sci. 2023, 14, 11872.
Teaching old presumptive tests new digital tricks with computer vision for forensic applications
Digital Discovery 2023, 2, 1143-1151.
Computer vision for non-contact monitoring of catalyst degradation and product formation kinetics
Chem. Sci. 2023, 14, 5323-5331 [2023 HOT Article collection]
Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena
Org. Proc. Res. Dev. 2022, 26, 3073−3088
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Publications
Links to all our papers (including all those from Marc's previous posts) are available below.
Independent and Collaborative Publications
41.
Synthesis of 2,6-trans-Tetrahydropyrans Using a Palladium-Catalyzed Oxidative Heck Redox-Relay Strategy
Org. Lett. 2024, DOI: 10.1021/acs.orglett.3c03866
40.
Directing Hydrogen Isotope Exchange with Aryl Carboxylic Acids
Synlett 2024, DOI: 10.1055/a-2239-6965
39.
Structure-guided design of a domain-selective bromodomain and extra terminal N-terminal bromodomain chemical probe
J. Med. Chem. 2023, 66, 15728.
38.
Computer Vision as a New Paradigm for Monitoring of Solution and Solid Phase Peptide Synthesis
Chem. Sci. 2023, 14, 11872.
37.
Teaching Old Presumptive Tests New Digital Tricks with Computer Vision for Forensic Applications
Digital Discovery 2023, 2, 1143.
36.
Computer vision for non-contact monitoring of catalyst degradation and product formation kinetics
Chem. Sci. 2023, 14, 5323. [2023 HOT Article collection]
35.
Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena
Org. Proc. Res. Dev. 2022, 26, 3073.
34.
3-Bromo-N,N,N-trimethylanilinium Iodide (1:1)
In Encyclopedia of Reagents for Organic Synthesis (EROS), 2022.
33.
A letter on rejection to my younger self
Nat. Rev. Chem. 2021, 5, 363.
32.
Trialkylammonium salt degradation: implications for methylation and cross-coupling
Chem. Sci. 2021, 12, 6949.
31.
Catalyst Design in C–H Activation: A Case Study in the Use of Binding Free Energies to Rationalise Intramolecular Directing Group Selectivity in Iridium Catalysis
Chem. Sci. 2021, 12, 6747
30.
Electrochemical Synthesis of Isoxazolines: Method and Mechanism
Chem. Eur. J. 2022, DOI:10.1002/chem.202103728
29.
A Transferable Psychological Evaluation of Virtual Reality Applied to Safety Training in Chemical Manufacturing
ACS Chem. Health Saf. 2021 28, 55.
28.
Iridium Catalysts for Hydrogen Isotope Exchange
Iridium Catalysts for Organic Reactions. Topics in Organomet. Chem., 2020, 69, p. 271-302.
27.
ACS Chem.Health Saf. 2020, 27, 263.
26.
Stereoselective Remote Functionalization via Palladium‐Catalyzed Redox‐Relay Heck Methodologies
Chem. Eur. J. 2020, 26, 1.
25.
Highlights: Reusing Masks, Face Covering Efficacy, Plant Restarts, and More
ACS Chem. Health Saf. 2020, 4, 204.
24.
A Mechanistic and Cautionary Case Study on the Use of Alternating Potential in Electrochemical Reactions
ChemElectroChem 2020, 7, 2771.
23.
Safety Highlights (Issue 3)
ACS Chem. Health Saf. 2020, 27, 148.
22.
Safety Highlight (Issue 2)
ACS Chem. Health Saf. 2020, 27, 86.
21.
The Piper Alpha Disaster: A Personal Perspective with Transferrable Lessons on the Long-Term Moral Impact of Safety Failures
ACS Chem. Health Saf. 2020, 27, 88.
20.
Safety Highlights (Issue 1)
ACS Chem. Health Saf. 2020, 27, 71.
19.
Motivations for Developing Safer Chemistry
Nature Chem. 2019, 12, 7.
18.
Charting the Course of Chemistry
Nature Chem. 2019, 11, 286.
17.
C−H Functionalisation for Hydrogen Isotope Exchange
Angew. Chem. Int. Ed. 2017, 57, 3022.
16.
Deuterium‐ and Tritium‐Labelled Compounds: Applications in the Life Sciences
Angew. Chem. Int. Ed. 2017, 57, 1758.
Marc's Postdoc Publications
15.
Anion-Initiated Trifluoromethylation by TMSCF3: Deconvolution of the Siliconate-Carbanion Dichotomy by Stopped-Flow NMR/IR
J. Am. Chem. Soc. 2018, 140, 11112.
14.
Base-Catalyzed Aryl-B(OH)2 Protodeboronation Revisited: From Concerted Proton Transfer to Liberation of a Transient Aryl Anion
J. Am. Chem. Soc. 2017, 139, 13156.
Marc's PhD Publications
13.
Computationally-Guided Development of a Chelated NHC-P Iridium(I) Complex for the Directed Hydrogen Isotope Exchange of Aryl Sulfones
ACS Catal. 2020, 10, 11120.
12.
The Natural Product Lepidiline A as an N-Heterocyclic Carbene Ligand Precursor in Complexes of the Type [Ir(cod)(NHC)PPh3)]X: Synthesis, Characterisation, and Application in Hydrogen Isotope Exchange Catalysis
Catalysts 2020, 10, 161.
11.
Iridium-catalyzed Csp3-H Activation for Mild and Selective Hydrogen Isotope Exchange
ACS Catal. 2018, 8, 10895.
10.
Iridium‐catalyzed Formyl‐Selective Deuteration of Aldehydes
Angew. Chem. Int. Ed. 2017, 56, 7808.
9.
Site-Selective Deuteration of N-Heterocycles via Iridium-Catalyzed Hydrogen Isotope Exchange
ACS Catal. 2017, 7, 7182.
8.
Iridium-catalysed ortho-H/D and -H/T exchange under basic conditions: C–H activation of unprotected tetrazoles
Chem. Commun. 2016, 52, 6669.
7.
Hydrogen isotope exchange with highly active iridium(I) NHC/phosphine complexes: a comparative counterion study
J. Label. Compd. Radiopharm. 2016, 59, 601.
6.
Iridium-Catalysed ortho-Directed Deuterium Labelling of Aromatic Esters—An Experimental and Theoretical Study on Directing Group Chemoselectivity
Molecules 2015, 20, 11676.
5.
Iridium-Catalyzed C–H Activation and Deuteration of Primary Sulfonamides: An Experimental and Computational Study
ACS Catal. 2015, 5, 402.
4.
Expanded applicability of iridium(I) NHC/phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles
Tetrahedron 2015, 71, 1924.
3.
Anion effects to deliver enhanced iridium catalysts for hydrogen isotope exchange processes
Org. Biomol. Chem. 2014, 12, 7927.
2.
The Synthesis of Highly Active Iridium(I) Complexes and their Application in Catalytic Hydrogen Isotope Exchange
Adv. Synth. Catal. 2014, 356, 351.
1.
Application of neutral iridium(I) N‐heterocyclic carbene complexes in ortho‐directed hydrogen isotope exchange
J. Label. Compd. Radiopharm. 2013, 56, 451.
Current Team
Tim McCabe
Henry ‘Barry’ Barrington
Calum Fyfe
Hayley Russell
Kristin Donnachie
Alana Gallacher
Dilyana Stoycheva
Alumni
Morven Gray
Ifeka (Fifi) Ugbolue
Marina Gladkikh
Chunhui Yan
Veronicah Gitome
Fabian Salge
Nicole McGrath
Daniel McCluskey
Cameron Oliver
Ciaran Griffin
Humair Saddiq
Jake McGuire
Nathalie Bugeja
Jamie Longino
Luke Whitaker
Holly Bonfield
Alfie Wills
Sam Holman
Jack Washington
David McKinney
Ross Hryczanek
Catherine Farrelly
Martin Kollie
Mhairi Gibson
Calum Howcutt
Neil McFarlane
Erin Bradley
Monica Chandwani Chandwani
Ben Clark
Ellis Cruickshank
Group News
Follow Reid Group Research on Twitter.
Congratulations, Dr Yan!
August, 2022
After 5 years of wonderful investment in the team, Dr Chunhui Yan completed his PhD. He heads back to China with his wife for life’s next adventure!
Marc wins the IChemE Hanson medal!
February, 2022
Marc’s efforts to bring long-term thinking to process safety earned him the medal, “awarded to the author of the best article to appear in The Chemical Engineer magazine each year.
Chunhui selected to present at STEM for Britain!
January, 2022
We're excited to hear that our very own Chunhui Yan has been selected to present his work during the 2022 gathering at Parliament in London. Congratulations, Chunhui!.
Holly & Chunhui Selected Among Young Chemist Top 10!
November, 2021
We are absolutely thrilled to see both Holly Bonfield and Chunhui Yan be selected among the Top 10 for the Scientific Update Young Chemist Award. Both will present their work during the 7th Winter Process Chemistry Conference in Leeds on 7-8 Dec.
Congratulations, Dr Whitaker!
October, 2021
We’re delighted to see early group associate Luke Whitaker pass his final PhD viva on Tuesday, 26th October! Following his Strathclyde-GSK PhD, Luke joined Illumina. Good luck, Luke!
Welcome, Barry!
October, 2021
We're delighted to welcome Henry 'Barry' Barrington to the team. Barry joins us for his PhD research having completed his MSci in Chemical Physics at the University of Bristol.
Welcome, Jake!
July, 2021
We are delighted to welcome Dr Jake McGuire to the team as our first #UKRIFLF-funded postdoc! Jake joins us following a PhD in the Sproules group at the University of Glasgow.
Alfie wins the RSC’s Sheelagh Campbell award !
April, 2021
Alfie has been recognized for his PhD contributions to electrochemistry, following his published work in ChemElectroChem! Alfie is part of the Strathclyde-GSK MPhil/PhD Programme & Doctoral Training Centre.
New UKRI-funded positions available!
February, 2021
As part of Marc’s new fellowship, we are offering several positions at the PhD, postdoctoral, and software engineer levels. Head over to the Work with Us page to learn more.
Marc awarded UKRI Future Leaders Fellowship!
October, 2020
Marc has been awarded a prestigious UKRI Future Leaders Fellowship to drive new computer vision methods for chemical kinetics applications!
Alfie’s GSK 1st year prize!
January, 2020
Many congratulations to Alfie Wills, who has won the Strathclyde-GSK prize for his 1st year PhD work in mechanistic analysis of electrochemical reactions. Well done, Alfie!
Holly wins SCI poster prize!
December, 2019
Congratulations, once again, to our own Holly Bonfield! A second gong from @SCIYoungChem!
Jack wins RSC travel grant to travel to ACS San Diego!
July, 2019
Thanks to @RoySocChem for awarding Jack Washington with a generous Travel Grant to participate in #ACSSANDIEGO. Congratulations, Jack!
Holly becomes a SCI Scholar!
July, 2019
Congratulations to Holly Bonfield on becoming one of three new SCI Scholars! Holly has previously worked in photoredox catalysis and is now studying (in her Strathclyde-GSK PhD programme) some key challenges in the catalytic formation of remote stereocentres.
Marc is nominated as Innovator of the Year
March, 2019
Marc was recognised by Strathclyde’s Entrepreneurial Network for his safety business developments. Great to be in the running with some of Strathclyde’s most exciting business stories!
Marc joins Strathclyde Rising Stars programme
September, 2018
Marc will be spending the next six months exploring the finer details of getting a business of the ground. This exciting program will help Reid Group Research commercialise some of our technological investigations.
Marc returns to Edinburgh to present at RSC Storytelling event
September, 2018
Marc presented a personal story of what drives his passion for research in safety training. Following the inaugural event at ACS NOLA earlier the same year, Marc switched gears from effective leadership to talk about his father’s experience of the Piper Alpha Disaster. Click on the photo to read Marc’s article on the topic.
Jack wins SCI writing contest!
September, 2018
Jack Washington was named overall winner of the Society of Chemical Industry writing competition. Jack wrote an engaging article about his Strathclyde-GSK PhD work on understanding the degradation of valuable organic molecules on the manufacturing scale. Click on the photo to read Jack’s article on the SCI website.
Jack joins the Dial-a-Molecule Summer School
July, 2018
Jack Washington visited Loughborough to learn about Design of Experiments, 3D Printing, Reactor Design, and Kinetics. We thank the Dial-a-Molecule team for supporting Jack’s application. Loads of valuable skills coming back to Reid Group Research.
Neil brings Carnegie support full circle for Marc
May, 2018
Neil McFarlane joined Reid Group Research on a Carnegie Trust Vacation Scholarship. Ten years previously, Marc started his academic career with the same undergraduate award. Click Neil’s photo to find out more.
Marc presents business pitch for Converge Challenge 2018
June, 2018
One stage, one mic, one minute. Marc joined 29 other aspiring entrepreneurs to present their quick fire business pitch at the Converge Challenge Top 30 dinner in Edinburgh.
Swimming with sharks at #ACSNOLA
March, 2018
Marc joined fellow RSC members on the opening day of the ACS National Meeting in New Orleans to deliver a personal story connected with Reid Group Research at the RSC Welcome Event. Click the photo to read more.
Marc joins the ACS on Campus team for a UK tour
February, 2018
Marc joined the ACS outreach team to tell students and postdocs at Oxford, UCL, and Imprerial College about the experience of being a SciFinder Future Leader, and to tell stories about how SciFinder had featured in Marc’s career to date.
Chunhui completes his MSc!
November, 2017
Congratulations to Chunhui Yan. The 1st MSc through @Reid_Research!
Marc wins best PhD thesis prize
April, 2017
Having previously won sister awards for 1st and 2nd year PhD reports, Marc has now won Strathclyde’s Prof. Patrick D. Ritchie Prize for his PhD thesis entitled: On the Design and Further Applications of Iridium(I) Complexes in Hydrogen Isotope Exchange Processes.
In a bonus historical coincidence, both Marc and Professor Patrick D. Ritchie were Carnegie PhD Scholars in Chemistry!
Lab set-up begins…
March, 2017
Following Marc’s secondment to LJMU, lab set-up got underway in the Thomas Graham Building at the University of Strathclyde. The synthesis lab shown here will house the group’s research on methylation reaction mechanisms and new technologies for reaction monitoring.
Marc joins Leach group for RSC Mobility Grant collaboration
February, 2017
Marc has joined Andrew G. Leach in Liverpool John Moores University for a six-week secondment, focussing on cheminformatics and Big Data techniques.
Marc joins Strathclyde on an Early Career Fellowship
January, 2017
Marc has won a 3-year Leverhulme Trust Early Career Fellowship to begin independent research at the University of Strathclyde, generously co-sponsored by GlaxoSmithKline. Marc's group will be pursuing methylation chemistries and enabling technologies for reaction monitoring.
Available Positions
Marc is supporting applications from self-funded candidates at all levels.
Open funded positions are detailed below, when available.
If you have a question or enquiry, you can reach out using the form below.
Enquiry for Reid Group Research
Funding and Sponsorship
Reid Group Research is forever thankful to the following funding bodies. Without their support, our work would be far more difficult!
